Effect of AGEs on Human Disc Herniation: Intervertebral Disc Hernia Is Also Effected by AGEs.

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Effect of AGEs on human disc herniation: intervertebral disc hernia is also effected by AGEs.

Currently, extracellular matrix MMP has been discussed in relation to the extrusion and spontaneous regression of the herniated mass observed in lumbar disc herniation. However, the question remains as to whether degenerated protein is really the cause of this condition's pathogenesis. We confirmed immunologically by means of electron microscopy that extrusion is caused by the AGEs (advanced gl...

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Intervertebral Disc Herniation: Pathophysiology and Emerging Therapies

Approximately 2.6 % of the US population visits a physician for treatment of spinal disorders annually (Fraser 2009 ) with costs of $7.1 billion from lost work days alone (Ricci et al. 2006 ) . “Herniation” of the intervertebral disc is one of the several spinal disorders that contribute to this very high incidence, with potential to cause signi fi cant pain, neurological de fi cit, and functio...

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Effects of Morphine Dependency on Intervertebral Disc in the Rat

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ژورنال

عنوان ژورنال: The Kurume Medical Journal

سال: 2002

ISSN: 0023-5679,1881-2090

DOI: 10.2739/kurumemedj.49.7